Early Warning Signs of Kidney Disease You Shouldn’t Ignore

Chronic kidney disease (CKD) is often called a “silent” condition because the kidneys can lose a large share of their function before you feel anything at all. That is exactly why knowing the subtle early signs, and getting tested if you are at risk, matters so much.

Subtle early signs to watch for

• Unusual fatigue. As kidney function declines, waste and the hormone changes of anemia can leave you persistently tired.
• Swelling (edema). Puffiness in the ankles, feet, hands, or around the eyes can reflect fluid and protein the kidneys are no longer balancing.
• Foamy urine. Persistent foam can be a sign of protein leaking into the urine.
• Changes in urination. Going more often at night, or producing more or less urine than usual, can be early clues.
• Trouble sleeping, itching, or poor appetite. A buildup of waste products can disturb sleep, cause itchy skin, and dull appetite.
• High blood pressure. New or worsening hypertension is both a cause and a consequence of kidney disease.

The two tests that catch it early

Most early kidney disease is found not from symptoms but from two simple, inexpensive tests:

• eGFR — a blood test that estimates how well your kidneys filter.
• Urine albumin-to-creatinine ratio (uACR) — a urine test that detects protein leaking into the urine, frequently the very first sign of damage.

Who should be tested

Ask your physician about kidney testing if you have diabetes, high blood pressure, heart disease, a family history of kidney disease, or are over 60. These groups carry the highest risk, and early detection is the single best tool we have to change the course of the disease.

The good news

When kidney disease is found early, there is a great deal that can be done — blood pressure and blood sugar control, modern kidney-protective medications, and dietary changes can all slow progression significantly. The earlier the conversation starts, the more options you have.

This article is general educational information and is not a substitute for personalized medical advice. If you have concerns about your kidney health, please speak with a physician.